Pharmacometrics Committee
IATDMCT Pharmacometrics Committee
(formerly known as Clinical Pharmacokinetics Committee.
Name changed December 2009.
Committee merged with the Pharmacoeconomics Committee, May 2010)
(formerly known as Clinical Pharmacokinetics Committee.
Name changed December 2009.
Committee merged with the Pharmacoeconomics Committee, May 2010)
Chair: franck.saint-marcoux@unilim.frFranck Saint-Marcoux, France
Vice-chair: Paula Schaiquevich, Argentina
Vice-chair: Paula Schaiquevich, Argentina
Background/purpose of the committee:
Pharmacometrics is the science of Quantitative Pharmacology that uses models based on pharmacology, physiology and disease for the quantitative analysis of interactions between drugs and patients. This involves pharmacokinetic (PK), pharmacodynamics (PD), pharmacogentics (PG), and disease progression with a focus on populations and variability.
Pharmacometricians are clinical scientists applying such mathematical and statistical methods to drug therapy with the aim of predicting the concentration time profile and total drug exposure (Area under the Curve, AUC) and its associations with physiologic effects and clinical outcomes.
In the clinical setting, Pharmacometrics aims at obtaining a better response with minimal adverse events in each individual.
The committee promotes:
- Communication between scientists of all disciplines involved in Pharmacometrics.
- Effective use of computer applications and their delivery at the clinical interface.
- The utilisation of cost-effectiveness and cost-utility models to justify its use in daily patient care.
Activities of the committee:
To actively participate in national and international fora on therapeutic drug monitoring and clinical pharmacokinetics.
To develop methods for studying the cost-effectiveness of Therapeutic Drug Monitoring.
To develop ideas for committee activities.
Pharmacometrics is the science of Quantitative Pharmacology that uses models based on pharmacology, physiology and disease for the quantitative analysis of interactions between drugs and patients. This involves pharmacokinetic (PK), pharmacodynamics (PD), pharmacogentics (PG), and disease progression with a focus on populations and variability.
Pharmacometricians are clinical scientists applying such mathematical and statistical methods to drug therapy with the aim of predicting the concentration time profile and total drug exposure (Area under the Curve, AUC) and its associations with physiologic effects and clinical outcomes.
In the clinical setting, Pharmacometrics aims at obtaining a better response with minimal adverse events in each individual.
The committee promotes:
- Communication between scientists of all disciplines involved in Pharmacometrics.
- Effective use of computer applications and their delivery at the clinical interface.
- The utilisation of cost-effectiveness and cost-utility models to justify its use in daily patient care.
Activities of the committee:
To actively participate in national and international fora on therapeutic drug monitoring and clinical pharmacokinetics.
To develop methods for studying the cost-effectiveness of Therapeutic Drug Monitoring.
To develop ideas for committee activities.
Membership list (Dec 2009):
Alison Thomson, Benedetta Sallustio, Ehab el Desoky, Guillermo Bramugia, Ken Ilett, Kees Neef, Kimikazu Shinozaki, Li Wang, Michael Neely, Philip Patsalos, Guido Paolo Caceres, Pierre Marquet, Raman Venkat, Ray Morris, Roger Jelliffe, Samantha Carmichael, Sander Vinks, Shareen Cox, Ysobel Gourlay, Zul Verjee, Iona MacDonald, Edgar Spencer, Reinier van Hest, Jeff Barrett, Duan Jingli, Hundie Tesfaye, Catherine Sherwin, Tsuyoshi Fukuda, Yoriko Harigaya, Jodi Courtney, Sal Salamone
The following documents are available to IATDMCT members:
Report to the membership Annual Meeting
October 8, 2009, Montreal Quebec
Report to the membership Annual Meeting
September 14, 2007, Nice France
