International Association of
Therapeutic Drug Monitoring and Clinical Toxicology
Fostering education, research and practice in TDM and CT

Immunosuppressive Drugs Committee

Stein Bergan

Chair

Stein Bergan
Oslo, Norway

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Scientific Committees
Immunosuppressive Drugs Committee

Satohiro Masuda

Vice-Chair

Satohiro Masuda
Chiba, Japan

Background & Purpose of the Committee

  • To provide evidence-based recommendations for TDM of immunosuppressive agents.
  • To promote the knowledge and understanding of immunosuppressive drug analysis and interpretation of results.
  • To enhance communication between scientists and physicians of all disciplines involved in TDM of immunosuppressive drugs.
  • To encourage the effective application of TDM in transplant medicine, with the aim of optimizing clinical drug use and maximizing the clinical and economic benefits.

Activities Planned/Committee Initiatives Currently in Progress

  • Preparation of a new consensus paper; entitled Mycophenolate Personalized Therapy: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology; in progress.
  • A satellite symposium, Update on mycophenolate, was suggested, accepted and planned for the IATDMCT-meeting in Banff 2020. This symposium may now be suggested for the next opportunity, e.g. Rome 2021.
  • To establish a course in TDM related to transplantation. This will be a course to follow online. The initiative is by D.J.A.R Moes and supported by current chair and vice chair of the ISD-SC. This project is in an early phase, and we are investigating options like integration into an already established course or to establish a new, separate course on this topic. A group of members will be recruited to develop the course. (Directors of education in the IATDMCT are informed.)
  • The online forum for the IATDMCT has been discontinued. The ISD-SC is a relatively large group and some kind of forum may be useful to facilitate communication. The setup of a dedicated forum for this committee is under consideration.

Past Years' Activities Held/Committee Initiatives

See publications list below.

Publications, Scientific Contributions

  • Publication in TDM Pharmacologic Treatment of Transplant Recipients Infected With SARS-CoV-2: Considerations Regarding Therapeutic Drug Monitoring and Drug–Drug Interactions. Elens & al.
  • Publication in TDM Measuring Intracellular Concentrations of Calcineurin Inhibitors: Expert Consensus from the International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) Expert Panel. Lemaitre & al.
  • Publication in Compass: Report on the symposium therapeutic drug monitoring of immunosuppressants: clinical challenges and analytical issues at the 16th congress of the Asian society of transplantation. S. Pattanaik.
  • Publication in Compass: The potential of the IATDMCT Scientific Committees. S. Bergan.

Additional Committee Resources

  • Biomarker Working Group (Leader U.Christans).
  • Standardization of ISD TDM Working Group. (Leaders: C. Seeger, L. Langman).
    Joint committee with IFCC is established.
  • Intracellular tacrolimus measurement Working Group. (Leader: F. Lemaitre).

Minutes of Committee Meetings